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1

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

Dheda, Keertan, Gumbo, Tawanda, Maartens, Gary, Dooley, Kelly E, McNerney, Ruth, Murray, Megan, Furin, Jennifer, Nardell, Edward A, London, Leslie, Lessem, Erica, Theron, Grant, van Helden, Paul, Niem

Journal:

The Lancet Respiratory Medicine

Year:

2017

Language:

english

File:

PDF, 8.02 MB

english, 2017

2

Cool but dangerous: How climate change is increasing the risk of airborne infections

Nardell, Edward, Lederer, Philip, Mishra, Hridesh, Nathavitharana, Ruvandhi, Theron, Grant

Journal:

Year:

2020

Language:

english

File:

PDF, 367 KB

english, 2020

3

Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?

Theron, Grant, Peter, Jonny, Dowdy, David, Langley, Ivor, Squire, S Bertel, Dheda, Keertan

Journal:

The Lancet Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 160 KB

english, 2014

4

False positive Xpert MTB/RIF results in re-tested patients with previous tuberculosis: frequency, profile, and prospective clinical outcomes

Theron, Grant, Venter, Rouxjeane, Smith, Liezel, Esmail, Aliasgar, Randall, Philippa, Sood, Vishesh, Oelfese, Suzette, Calligaro, Greg, Warren, Robin, Dheda, Keertan

Journal:

Journal of Clinical Microbiology

Year:

2018

Language:

english

File:

PDF, 959 KB

english, 2018

5

Test characteristics and potential impact of the urine LAM lateral flow assay in HIV-infected outpatients under investigation for TB and able to self-expectorate sputum for diagnostic testing

Peter, Jonny, Theron, Grant, Chanda, Duncan, Clowes, Petra, Rachow, Andrea, Lesosky, Maia, Hoelscher, Michael, Mwaba, Peter, Pym, Alex, Dheda, Keertan

Journal:

BMC Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 963 KB

english, 2015

6

Cost-effectiveness of Xpert MTB/RIF and investing in health care in Africa

Dheda, Keertan, Theron, Grant, Welte, Alex

Journal:

The Lancet Global Health

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

7

Xpert MTB/RIF Results in Patients With Previous Tuberculosis: Can We Distinguish True From False Positive Results?

Theron, Grant, Venter, Rouxjeane, Calligaro, Greg, Smith, Liezel, Limberis, Jason, Meldau, Richard, Chanda, Duncan, Esmail, Aliasgar, Peter, Jonny, Dheda, Keertan

Journal:

Clinical Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 357 KB

english, 2016

8

Mycobacterial genomic DNA from used Xpert MTB/RIF cartridges can be utilised for accurate second-line genotypic drug susceptibility testing and spoligotyping

Venter, Rouxjeane, Derendinger, Brigitta, de Vos, Margaretha, Pillay, Samantha, Dolby, Tanya, Simpson, John, Kitchin, Natasha, Ruiters, Ashley, van Helden, Paul D., Warren, Robin M., Theron, Grant

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.63 MB

english, 2017

9

Drug-Associated Adverse Events and Their Relationship with Outcomes in Patients Receiving Treatment for Extensively Drug-Resistant Tuberculosis in South Africa

Shean, Karen, Streicher, Elizabeth, Pieterson, Elize, Symons, Greg, van Zyl Smit, Richard, Theron, Grant, Lehloenya, Rannakoe, Padanilam, Xavier, Wilcox, Paul, Victor, Tommie C., van Helden, Paul, Gro

Journal:

Year:

2013

Language:

english

File:

PDF, 441 KB

english, 2013

10

Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation

Pooran, Anil, Theron, Grant, Zijenah, Lynn, Chanda, Duncan, Clowes, Petra, Mwenge, Lawrence, Mutenherwa, Farirai, Lecesse, Paul, Metcalfe, John, Sohn, Hojoon, Hoelscher, Michael, Pym, Alex, Peter, Jon

Journal:

The Lancet Global Health

Year:

2019

Language:

english

File:

PDF, 616 KB

english, 2019

11

Extract from used Xpert MTB/RIF Ultra cartridges is useful for accurate second-line drug-resistant tuberculosis diagnosis with minimal rpoB-amplicon cross-contamination risk

Venter, Rouxjeane, Minnies, Stephanie, Derendinger, Brigitta, Tshivhula, Happy, de Vos, Margaretha, Dolby, Tania, Ruiters, Ashley, Warren, Robin M., Theron, Grant

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.78 MB

2020

12

Blood transcriptional biomarkers for active pulmonary tuberculosis in a high-burden setting: a prospective, observational, diagnostic accuracy study

Turner, Carolin T, Gupta, Rishi K, Tsaliki, Evdokia, Roe, Jennifer K, Mondal, Prasenjit, Nyawo, Georgina R, Palmer, Zaida, Miller, Robert F, Reeve, Byron WP, Theron, Grant, Noursadeghi, Mahdad

Journal:

The Lancet Respiratory Medicine

Year:

2020

Language:

english

File:

PDF, 1.04 MB

english, 2020

13

Cost-effectiveness of post-treatment follow-up examinations and secondary prevention of tuberculosis in a high-incidence setting: a model-based analysis

Marx, Florian M, Cohen, Ted, Menzies, Nicolas A, Salomon, Joshua A, Theron, Grant, Yaesoubi, Reza

Journal:

The Lancet Global Health

Year:

2020

File:

PDF, 1.28 MB

2020

14

ArgR–promoter interactions in Corynebacterium glutamicum arginine biosynthesis

Grant Theron, Sharon J. Reid

Journal:

Biotechnology and Applied Biochemistry

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

15

Postcardioplegic Myocardial Recovery: Effects of Halothane, Nifedipine, HOE 694, and Quinacrine

Amanda Lochner, Sonia Genade, Erna Tromp, Salomine Theron, Grant Trollip

Journal:

Cardiovascular Drugs and Therapy

Year:

1998

Language:

english

File:

PDF, 343 KB

english, 1998

16

Geochemistry and palaeogeography of upper Ordovician glaciogenic sedimentary rocks in the Table Mountain Group, South Africa

Grant M. Young, W.E.L. Minter, J.N. Theron

Journal:

Palaeogeography, Palaeoclimatology, Palaeoecology

Year:

2004

Language:

english

File:

PDF, 1.37 MB

english, 2004

17

Xpert MTB/RIF test for tuberculosis

Grant Theron, Jonny Peter, Keertan Dheda

Journal:

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

18

Point-of-care diagnosis of tuberculosis: Past, present and future

DHEDA, KEERTAN, RUHWALD, MORTEN, THERON, GRANT, PETER, JONATHAN, YAM, WING CHEONG

Journal:

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

19

Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial

Theron, Grant, Zijenah, Lynn, Chanda, Duncan, Clowes, Petra, Rachow, Andrea, Lesosky, Maia, Bara, Wilbert, Mungofa, Stanley, Pai, Madhukar, Hoelscher, Michael, Dowdy, David, Pym, Alex, Mwaba, Peter, M

Journal:

Year:

2014

Language:

english

File:

PDF, 348 KB

english, 2014

20

Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis

Dheda, Keertan, Gumbo, Tawanda, Gandhi, Neel R, Murray, Megan, Theron, Grant, Udwadia, Zarir, Migliori, G B, Warren, Robin

Journal:

The Lancet Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

21

Comparison of two methods for acquisition of sputum samples for diagnosis of suspected tuberculosis in smear-negative or sputum-scarce people: a randomised controlled trial

Peter, Jonathan G, Theron, Grant, Pooran, Anil, Thomas, Johnson, Pascoe, Mellissa, Dheda, Keertan

Journal:

The Lancet Respiratory Medicine

Year:

2013

Language:

english

File:

PDF, 256 KB

english, 2013

22

Urine antigen test for diagnosis of HIV-associated tuberculosis

Peter, Jonathan G, Theron, Grant, Dheda, Keertan

Journal:

The Lancet Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 271 KB

english, 2012

23

Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-γ for the evaluation of pleural tuberculosis: a prospective cohort study

Meldau, Richard, Peter, Jonny, Theron, Grant, Calligaro, Greg, Allwood, Brian, Symons, Greg, Khalfey, Hoosain, Ntombenhle, Gina, Govender, Ureshnie, Binder, Anke, van Zyl-Smit, Richard, Dheda, Keertan

Journal:

BMC Pulmonary Medicine

Year:

2014

Language:

english

File:

PDF, 318 KB

english, 2014

24

Evaluation of the Xpert MTB/RIF Assay for the Diagnosis of Pulmonary Tuberculosis in a High HIV Prevalence Setting

Theron, Grant, Peter, Jonny, van Zyl-Smit, Richard, Mishra, Hridesh, Streicher, Elizabeth, Murray, Samuel, Dawson, Rodney, Whitelaw, Andrew, Hoelscher, Michael, Sharma, Surendra, Pai, Madhukar, Warren

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 917 KB

english, 2011

25

Xpert MTB/RIF as a Measure of Sputum Bacillary Burden. Variation by HIV Status and Immunosuppression

Hanrahan, Colleen F., Theron, Grant, Bassett, Jean, Dheda, Keertan, Scott, Lesley, Stevens, Wendy, Sanne, Ian, Van Rie, Annelies

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 790 KB

english, 2014

26

Cochrane Database of Systematic Reviews (Protocols) || The GenoType® MTBDR sl test for resistance to second-line anti-tuberculosis drugs

Year:

1996

Language:

english

File:

PDF, 600 KB

english, 1996

27

Cochrane Database of Systematic Reviews (Reviews) || The diagnostic accuracy of the GenoType ® MTBDR sl assay for the detection of resistance to second-line anti-tuberculosis drugs

Year:

1996

Language:

english

File:

PDF, 1.74 MB

english, 1996

28

Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous pericarditis compared to adenosine deaminase and unstimulated interferon-γ in a high burden setting: a prospective study

Pandie, Shaheen, Peter, Jonathan G, Kerbelker, Zita S, Meldau, Richard, Theron, Grant, Govender, Ureshnie, Ntsekhe, Mpiko, Dheda, Keertan, Mayosi, Bongani M

Journal:

Year:

2014

Language:

english

File:

PDF, 368 KB

english, 2014

29

Xpert MTB/RIF to diagnose tuberculosis in children

Journal:

The Lancet Respiratory Medicine

Year:

2015

Language:

english

File:

PDF, 97 KB

english, 2015

30

Automatic detection of tuberculosis in chest radiographs using a combination of textural, focal, and shape abnormality analysis

Hogeweg, Laurens, Sanchez, Clara, Maduskar, Pragnya, Philipsen, Rick, Story, Alistair, Dawson, Rodney, Theron, Grant, Dheda, Keertan, Peters-Bax, Liesbeth, van Ginneken, Bram

Journal:

IEEE Transactions on Medical Imaging

Year:

2015

Language:

english

File:

PDF, 6.74 MB

english, 2015

31

Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden

Mthiyane, Thuli, Rustomjee, Roxana, Pym, Alex, Connolly, Cathy, Onyebujoh, Philip, Theron, Grant, Dheda, Keertan

Journal:

International Journal of Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

32

Diagnostic Accuracy of Quantitative PCR (Xpert MTB/RIF) for Tuberculous Meningitis in a High Burden Setting: A Prospective Study

Patel, Vinod B., Theron, Grant, Lenders, Laura, Matinyena, Brian, Connolly, Cathy, Singh, Ravesh, Coovadia, Yacoob, Ndung'u, Thumbi, Dheda, Keertan, Boulware, David R.

Journal:

Year:

2013

Language:

english

File:

PDF, 403 KB

english, 2013

33

Burden of tuberculosis in intensive care units in Cape Town, South Africa, and assessment of the accuracy and effect on patient outcomes of the Xpert MTB/RIF test on tracheal aspirate samples for diagnosis of pulmonary tuberculosis: a prospective burden of disease study with a nested randomised controlled trial

Calligaro, Gregory L, Theron, Grant, Khalfey, Hoosain, Peter, Jonathan, Meldau, Richard, Matinyenya, Brian, Davids, Malika, Smith, Liezel, Pooran, Anil, Lesosky, Maia, Esmail, Aliasgar, Miller, Malcol

Journal:

The Lancet Respiratory Medicine

Year:

2015

Language:

english

File:

PDF, 377 KB

english, 2015

34

Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study

Theron, Grant, Peter, Jonny, Zijenah, Lynn, Chanda, Duncan, Mangu, Chacha, Clowes, Petra, Rachow, Andrea, Lesosky, Maia, Hoelscher, Michael, Pym, Alex, Mwaba, Peter, Mason, Peter, Naidoo, Pamela, Poor

Journal:

BMC Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 589 KB

english, 2015

35

Data for action: collection and use of local data to end tuberculosis

Theron, Grant, Jenkins, Helen E, Cobelens, Frank, Abubakar, Ibrahim, Khan, Aamir J, Cohen, Ted, Dowdy, David W

Journal:

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

36

Sensitivity of C-Tb: a novel RD-1-specific skin test for the diagnosis of tuberculosis infection

Hoff, Soren T., Peter, Jonathan G., Theron, Grant, Pascoe, Mellissa, Tingskov, Pernille N., Aggerbeck, Henrik, Kolbus, Daniel, Ruhwald, Morten, Andersen, Peter, Dheda, Keertan

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 420 KB

english, 2015

37

Should Xpert® MTB/RIF be rolled out in low-income countries? [Correspondence]

Peters, Dean, Theron, Grant, Peter, Jonny, Dheda, Keertan

Journal:

The International Journal of Tuberculosis and Lung Disease

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

38

Xpert MTB/RIF versus Sputum Smear Microscopy: Microscopy Needs a Level Playing Field

Theron, Grant, Peter, Jonny, Dheda, Keertan

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

39

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C60. ADVANCES IN DIAGNOSIS OF ACTIVE TUBERCULOSIS DISEASE - Comparison Of Quantitative Techniques Including Xpert MTB/RIF To Evaluate Mycobacterial Burden

Van Zyl-Smit, Richard N., Binder, Anke, Meldau, Richard, Mishra, Hridesh, Semple, Patricia L., Theron, Grant, Peter, Jonathan, Whitelaw, Andrew, Sharma, Surendra K., Warren, Robin, Bateman, Eric D., D

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

40

Cochrane Database of Systematic Reviews (Reviews) || GenoType ® MTBDR sl assay for resistance to second-line anti-tuberculosis drugs

Year:

1996

Language:

english

File:

PDF, 2.23 MB

english, 1996

41

Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments

Theron, Grant, Peter, Jonny, Calligaro, Greg, Meldau, Richard, Hanrahan, Colleen, Khalfey, Hoosain, Matinyenya, Brian, Muchinga, Tapuwa, Smith, Liezel, Pandie, Shaheen, Lenders, Laura, Patel, Vinod, M

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 914 KB

english, 2014

42

The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates

Tomasicchio, Michele, Theron, Grant, Pietersen, Elize, Streicher, Elizabeth, Stanley-Josephs, Danielle, van Helden, Paul, Warren, Rob, Dheda, Keertan

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 683 KB

english, 2016

43

Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial

Calligaro, Gregory L, Zijenah, Lynn S, Peter, Jonathan G, Theron, Grant, Buser, Virginia, McNerney, Ruth, Bara, Wilbert, Bandason, Tsitsi, Govender, Ureshnie, Tomasicchio, Michele, Smith, Liezel, Mayo

Journal:

The Lancet Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 388 KB

english, 2017

44

The diagnostic accuracy of pericardial and urinary lipoarabinomannan (LAM) assays in patients with suspected tuberculous pericarditis

Pandie, Shaheen, Peter, Jonathan G., Kerbelker, Zita S., Meldau, Richard, Theron, Grant, Govender, Ureshnie, Ntsekhe, Mpiko, Dheda, Keertan, Mayosi, Bongani M.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 695 KB

english, 2016

45

Drug-resistant tuberculosis in 2017: at a crossroads

Dowdy, David W, Theron, Grant, Tornheim, Jeffrey A, Kendall, Emily A

Journal:

The Lancet Respiratory Medicine

Year:

2017

Language:

english

File:

PDF, 121 KB

english, 2017

46

An automated tuberculosis screening strategy combining X-ray-based computer-aided detection and clinical information

Melendez, Jaime, Sánchez, Clara I., Philipsen, Rick H. H. M., Maduskar, Pragnya, Dawson, Rodney, Theron, Grant, Dheda, Keertan, van Ginneken, Bram

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 358 KB

english, 2016

47

Of Testing and Treatment: Implications of Implementing New Regimens for Multidrug-Resistant Tuberculosis

Dowdy, David W., Theron, Grant, Tornheim, Jeffrey A., Warren, Robin, Kendall, Emily A.

Journal:

Clinical Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 325 KB

english, 2017

48

Cryptic Micro-heteroresistance Explains M. tuberculosis Phenotypic Resistance

Metcalfe, John Z, Streicher, Elizabeth, Theron, Grant, Colman, Rebecca E, Allender, Christopher, Lemmer, Darrin, Warren, Rob, Engelthaler, David M

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2017

Language:

english

File:

PDF, 10.15 MB

english, 2017

49

A RAPID SEROLOGICAL TRIAGE TEST FOR DETECTING ACTIVE TUBERCULOSIS

Borain, Nick, Petersen, Lizette, Plessis, Julianne Du, Theron, Grant, Holm-Hansen, Carol

Journal:

BMJ Global Health

Year:

2017

Language:

english

File:

PDF, 63 KB

english, 2017

50

Mycobacterium tuberculosis subculture results in loss of potentially clinically relevant heteroresistance

Metcalfe, John Z., Streicher, Elizabeth, Theron, Grant, Colman, Rebecca E., Penaloza, Renee, Allender, Christopher, Lemmer, Darrin, Warren, Robin M., Engelthaler, David M.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017